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Bulletin Avonex Package Size Change Communication #78MG12 Date: September 5, 2012 Effective: September 26, 2012 Issue

IMPORTANT NOTICE THAT WILL IMPACT YOUR CLAIMS SUBMISSION PROCESS FOR AVONEX What You Need to Know Effective September 26, 2012, due to a recent review of Avonex products by NCPDP, the package size for NDC 59627-0002-05 will change as follows: NDC 59627-0002-05

Name Avonex Kit (prefilled syringe)

Old Pack Quantity 4

New Pack Quantity 1

To ensure you are properly submitting claims for payment, all Avonex claims will be reviewed for proper quantities after this change takes place. Pharmacies will be notified if claims have been submitted improperly. Claims may be denied if incorrect quantities are submitted after this change. Action Required Please review billing procedures for Avonex in preparation for this change. If you have any questions please contact the Argus Pharmacy Help Desk at 1-800-522-7487, which is available 24 hours a day/7 days a week.

©2012 by Argus Health Systems, Inc. All Rights Reserved. The computer systems, procedures, databases, software programs, documentation and other materials (collectively "Information") created, maintained or provided by Argus Health Systems, Inc. ("Argus"), are proprietary to Argus and are confidential. 78MG12