Clinical Chemistry ACS Symposium Series - American Chemical Society


Clinical Chemistry ACS Symposium Series - American Chemical Societypubs.acs.org/doi/pdf/10.1021/ac50029a770training prog...

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Clinical Chemistry ACS Symposium Series No. 36 Donald T. Forman and Richard W. Mattoon, Editors Based on the Annual Lecture Series co-sponsored by the Chicago Sections of the American Chemical Society and the American Association of Clinical Chemists. This new volume is a compendium of current information on topics that have a clinical chemical basis but which are also of interest to specialists in clinical areas such as pediatrics, endocri­ nology, and hematology. Ten chapters examine the etiology of disease and diagnosis as well as describe technical advances which can be applied more practically in the near future. Clinical chemists, biochemists, and hospital pathologists, universities, and training programs as well as medical specialists and laboratory technol­ ogists will find valuable material on: • separation and characterization of hemoglobins, measurement of calciotropic hormones, competitive protein binding assays • prenatal detection of genetic diseases, neonatology, blood gas abnormalities, clinical enzymology • modern liquid chromatography, trace metals in biological fluids, drug interference in laboratory testing

293 pages (1976) $19.75 clothbound LC 76-49983 ISBN 0-8412-0345-8

SIS/American Chemical Society 1155 16th St., N.W./Wash., D.C. 20036 Please send copies of SS 36 Clinical Chemistry at $19.75 per copy. Π Check enclosed for $ . D Bill me. Postpaid in U.S. and Canada, plus 40 cents elsewhere. Name Address City

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sants including the less-known and utilized compounds. Throughout the book, metabolite information is avail­ able if applicable to the particular an­ alytical method. The book for the most part is a re­ view of published analytical methods that are accurately documented. Few if any comments are original with the current authors. This is not recom­ mended as a textbook but would serve as an excellent reference book to cir­ cumvent extensive literature search­ ing for information relative to the analysis of biologic specimens for spe­ cific drugs.

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Fractionation of Synthetic Polymers. L. H. Tung, Ed. vii + 748 pages. Marcel Dekker, Inc., 270 Madison Ave., New York, N.Y. 10016. 1977. $69.50

Reviewed by John G. Cobler, Analyti­ cal Dept., Dow Chemical Co., Mid­ land, Mich. 48640 "Fractionation of Synthetic Poly­ mers" is a collection of seven indepen­ dently written chapters on the princi­ ples and practices of practical meth­ ods of polymer fractionation. E. F. Casassa authored the chapter on phase equilibrium in polymer solu­ tions. The thermodynamics of liquid mixtures are reviewed, and the simi­ larities and differences between mod­ els for simple mixtures and polymer solutions are discussed. The FloryHuggins lattice theory is used to de­ scribe phase separations in binary sys­ tems. Newer theories consider the noncombinatory entropy of mixing and appear to overcome some of the inadequacies of the Flory-Huggins treatment. The chapter concludes with a table of symbols. I t would have been helpful if the other authors had done likewise, particularly since the same symbols are not used through­ out. K. Kamide discusses the theory and principles of molecular weight frac­ tionation in binary systems by succes­ sive precipitation and successive solu­ tion. Experimental and computer sim­ ulation calculations are reported. Un­ fortunately, 50 pages of figures are in­ serted in the center of the chapter. I found it difficult to maintain a conti­ nuity of thought when searching through 50 pages to find a figure relat­ ed to the text discussion. E. M . Barrall I I , J. F. Johnson, and A. R. Cooper prepared the chapter on column chromatography. The authors state that a detailed review has been sacrificed in order to present a coher­ ent picture of the method that could be useful to the experimentalist, an undertaking that was successfully ac­ complished. The chapter reviews in-

For storage and research using costly micro samples. The cone-shaped interiors of Wheaton Micro Product Vials as­ sure total downward drainage, permitting maximum retrieval of contents by syringe or pipette. Wasting of expensive material is eliminated. Vials are exception­ ally sturdy. Use them for small scale reactions, centrifugation and shipping, as well as storage. Available with screw caps or septa and aluminum seals in sizes from 0.1 ml to 5 ml. The 0.1 ml size fits standard auto samplers. Wheaton "200" brand borosilicate glass pro­ vides exceptional thermal and chemical endurance. Safeguards the integrity of the product against changes in pH. Vials and caps can be autoclaved. O r d e r t h r o u g h Cole-Parmer Instru­ ment Co., Dynalab Corp., Fisher Scientific Co., Markson Science Inc., Rochester Scientific Co., Inc., Scientific Products, Wilkens-Anderson Company a n d O t h e r

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ANALYTICAL CHEMISTRY, VOL. 50, NO. 7, JUNE 1978 · 681 A