clinical study

---

® SymGlucan MULTI-FUNCTIONAL ANTI-AGING INGREDIENT new clinical study data

CLINICAL STUDY Protocol > Panel of 10 female subjects > Test area: inner side of forearms > Test period: 4 weeks > Test Products: emulsion with 5% SymGlucan® and placebo > Frequency of application: twice daily • Measurements: • Moisture – Corneometer • Firmness, Elasticity – Cutometer • Roughness (smoothness) – PRIMOS (Phase-shifting Rapid In-vivo Measurement of Skin)

2

CLINICAL STUDY Skin Moisture

relative to untreated (%)

Increase in moisture

25 20

*

* * p < 0.05

15

Placebo 5% SymGlucan

10 5 0

2 weeks

4 weeks

3

CLINICAL STUDY Skin Firmness

relative to untreated (%)

Increase in firmness

20 15

Placebo

10

5% SymGlucan

5 0 -5

2 weeks

4 weeks

4

CLINICAL STUDY Skin Elasticity

relative to untreated (%)

Increase in elasticity

12

8

Placebo 5% SymGlucan

4

0

-4

2 weeks

4 weeks

5

CLINICAL STUDY Skin Smoothness

relative to untreated (%)

Increase in smoothness

12 10

Placebo

8

5% SymGlucan 6 4 2 0

2 weeks

4 weeks

6

SUMMARY SymGlucan® increases skin’s: > Moisture > Firmness > Elasticity > Smoothness

7