Isopropyl Ether - ACS Reagent Chemicals (ACS Publications)

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Monograph pubs.acs.org/doi/book/10.1021/acsreagents

Isopropyl Ether (Diisopropyl Ether)

Downloaded by CORNELL UNIV on May 17, 2017 | http://pubs.acs.org Publication Date (Web): February 28, 2017 | doi: 10.1021/acsreagents.4182

Part 4, Monographs for Reagent Chemicals: General Descriptions, Specifications, and Tests eISBN: 9780841230460 Tom Tyner Chair, ACS Committee on Analytical Reagents James Francis Secretary, ACS Committee on Analytical Reagents

ABSTRACT This monograph for Isopropyl Ether provides, in addition to common physical constants, a general description including typical appearance, applications, change in state (approximate), and density. The monograph also details the following specifications and corresponding tests for verifying that a substance meets ACS Reagent Grade specifications including: Assay, Color (APHA), Peroxide, Residue after Evaporation, Titrable Acid. Special caution is advised for the handling or testing of this substance.

(C3H7)2O

Formula Wt 102.18

CAS No. 108-20-3

C a u t i o n : Isopropyl ether is a volatile and flammable liquid with a tendency to form an explosive peroxide. No evaporation or distillation should be performed unless peroxide is shown to be absent. Generally, a stabilizer is present to retard peroxide formation.

GENERAL DESCRIPTION Typical appearance . . . . . . . . Applications . . . . . . . . . . . . . Change in state (approximate) . Density . . . . . . . . . . . . . . . .

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clear liquid organic solvent; extracting solvent boiling point, 68 °C 0.73

SPECIFICATIONS Assay . . . . . . . . . . . . . . . . . . . . . . . . . . . . ≥99.0% (C3H7)2O

© 2017 American Chemical Society

A

ACS Reagent Chemicals ACS Reagent Chemicals; American Chemical Society: Washington, DC, 2017.

DOI:10.1021/acsreagents.4182 ACS Reagent Chemicals, Part 4

ACS Reagent Chemicals

Monograph

pubs.acs.org/doi/book/10.1021/acsreagents

Color (APHA) . . . . . . . . . Peroxide (as C6H14O2). . . . Residue after evaporation . Titrable acid . . . . . . . . .

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Maximum Allowable 25 0.05% 0.01% 0.0007 meq/g

TESTS Assay Analyze the sample by gas chromatography using the general parameters cited in [Part 2: Chromatography; Recommended Procedures; Gas Chromatography]. The following specific conditions are also required. Downloaded by CORNELL UNIV on May 17, 2017 | http://pubs.acs.org Publication Date (Web): February 28, 2017 | doi: 10.1021/acsreagents.4182

Column . . . . . . . . . . . . . . . . . . . . . . . . . . Type I, methyl silicone Measure the area under all peaks, and calculate the isopropyl ether content in area percent.

Color (APHA) [Part 2: Measurement of Physical Properties; Color (APHA); Procedure for Color (APHA)].

Peroxide Place 150 mL of 10% sulfuric acid in each of two 500 mL glass-stoppered Erlenmeyer flasks. Reserve one for a blank determination. Into the other, pipette 7.2 g (10 mL) of sample, and mix well. To each flask, add 0.15–0.25 mL of 1% ammonium molybdate solution and 15 mL of 10% potassium iodide reagent solution. Mix, and allow to stand in the dark for 15 min at room temperature. Titrate each with 0.05 N sodium thiosulfate until the yellow color begins to fade. Add 3 mL of starch indicator solution, and continue the titration just to disappearance of the blue color. Correct for a blank determination. One milliliter of 0.05 N sodium thiosulfate corresponds to 0.00296 g of (C3H7)2O2.

Residue after Evaporation [Part 2: Gravimetric Methods; Residue after Evaporation]. See the warning above. Evaporate 70 mL (50 g) of sample.

Titrable Acid Titrate 36 g (50 mL) with 0.02 N methanolic potassium hydroxide solution, with 0.15 mL of phenolphthalein indicator solution, to a pink end point that remains for at least 15 s. Not more than 1.25 mL of the methanolic potassium hydroxide should be required.

© 2017 American Chemical Society

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ACS Reagent Chemicals ACS Reagent Chemicals; American Chemical Society: Washington, DC, 2017.

DOI:10.1021/acsreagents.4182 ACS Reagent Chemicals, Part 4