After a survey revealed 95% of patients who had experienced nausea and vomiting from chemotherapy stated the side effect had caused an impact on their daily life at some point, we knew more could be done to support these patients. The Hematology/Oncology Pharmacy Association (HOPA), in partnership with Eisai Inc. and Helsinn Therapeutics (U.S.), Inc., have developed the action-oriented Time to Talk CINV Toolkit, created with input from pharmacists, nurses, patients and caregivers. The goal of the tools is to improve communication about the prevention of CINV.
TOOLKIT
Any member of the healthcare team can use the toolkit to improve patients’ understanding and experiences when receiving chemotherapy.
HEALTHCARE TEAM HOW-TO GUIDE
We welcome your feedback on patients’ experiences using these tools and can be contacted at
[email protected].
INCORPORATE THESE TOOLS INTO THE CONVERSATION WITH YOUR PATIENTS
REVIEW THE CINV PREVENTION BEST PRACTICES CHECKLIST CREATED FOR THE HEALTHCARE TEAM
INITIATE THE CONVERSATION WITH THE CINV COMMUNICATION CHECKLIST WHEN STARTING A PATIENT ON CHEMOTHERAPY CINV PREVEN
Communication within the healthcare team can be just as important as communication with patients.
BEST PRAC
TION TICES CHEC KLIST
Many patients undergoin believe it’s a side ef fe g chemotherapy are understan ct they “ju fearful of experienc d the importanc s t h av ing chemothe e of alerting e to live with.” They Patients do rapy-induc d o n ot k n their healthcare ed nausea the risk of not need to suffer needlessl team when ow that prevention and vomiting issues with they are experienc of CINV sho (CINV), as y from nausea treatment ul d b e t h e they This piece, ing these adherence along with side effects. expectation and ne , hospital and vomiting. With colleagues the other stays, and better communic e d to tools in the , and shared ER visits due Time to Talk via social to complicat ation and understan media. CINV toolkit, ions may be ding of this can be printed, reduced. side effect, filled out digitally, emailed to ESTABLISH patients and THERAP
EUTIC AND
COMMUNICATIO Inform your patients of N GOALS WITH the goal of and “no nausea” “no vomiting” following chemothe PATIENTS Ask your patients rapy Educate on the risks of what they where to start a n d vo m i t i already know “pushing through” ng, like de the conversat so you know nausea hy d r a t i o n admission ion about a n d h o sp i , and the importanc CINV Share tools t al about side available to e of communic effects effects: help patients ating report their C o m m u ni c side • Time to a te s t r a te g Talk CINV ie s f o r p r o adherence Chemothe Effect Tracker p e r m e di c rapy Side a t io n • The MASCC Antiemesi s Tool app www.masc available at c.org/mat
INSTITUTE THERAPEUTIC HEALTHCARE AND COMMU TEAM NICATION GOALS WITHIN
Review this checklist with your team as a reminder of the most important things to do to ensure clear communication about CINV
Determine patient risk factors for considerin g treatment CINV when : • Below age 50 • Female
COMMUNICATIO
N CONTIN Confirm your UES OUTSID patients know to contact when and E THE DOCTOR on whom experiencing the healthcare team ’S OFFICE if they are Provide outside nausea and/or chemothe resources vomiting from rapy advocacy organizations, such as books, patient the Time to local peer-to-pe Determine Talk CINV™ if there is er groups, toolkit a caregiver active role and • For more that in treatment informatio communic who should plays an n on Time ations the Hematolo be included to Talk gy/Oncolo in (HOPA) website gy Pharmacy CINV, visit Advise patients Associatio at www.Time to set up appointme Resources ToTalkCINV.com. n appropriat include: e support nts with providers navigator, oncology pharmacis such as a nurse social worker t, and/or oncology Make patients aware of resources available to all hospital/institution them THE R E AR E WAYS TO AND VOMITING PR E VE NT NAUS FR
EA OM CHE MOTHE AND IT S TAR TS WITH R APY A CONVE R S ATION Nauseaandvom iting som eth effe f chem t shou areside honest ingtha otherapytha ma inthewacytsofoyou rsationsldgetyo ybeprevente canleadcotonve ur h althcareterachemotherapy. tIt’s better carewoith defin lynot m. Talkingtothe soimportant tod.hIt’s throughch f your nae use emothera avefrequite about chemothera pytreatm ent nd ent. aandvomiting. Inturn, tham ysideeffeacts t couldle adtoaneapsie GET THE CONVERSATION r journey STARTED Your healthcarete amisheretohe lp. At your nextapp ointment, bring thispagewithyo uandtakenotes BEFORE STARTING asyoutalktoyo ur healthcarete CHEMOTHERAPY am: What arethepossi chemotherapy? blesideeffectsof my Consideringthetyp DoI haveanyris howlikelyisit th eof chemotherapyI a or less elytohkfactorsthat might mak at I willexperience mreceiving, em ave vomiting? chemothliekra nauseaand py? nauseaandvomitingfroemmore Howdoyoudecid mynauseaandvoewhat treatment touseto miting? prevent PREVENTING NAUSEA AND VOMITING FROM Thissectio clu des fromchemonthin CHEMOTHERAPY erapy. questionsyoucanaskyour healt hcareteamabou t medicationsfor Whichantinausea thetreatment of dvomitingtreatm nauseaandvom thinkI sh ouldbetaaknin iting gandwhy? ent doyou WhenshouldI st If I doh art takingmytre I do? avenauseaand/or vomiting, wha atment? HowshouldI tak t should emytreatment? What info ation Withthistreatme uldbehelpful for haveif rm nt, what shouldI oexperiewo youto chemothIedra expect tohappen What aresomeo py? ncenauseaandvomitingfrom ? f thepossiblesid treatment? Arethere rtain eeffectsof my fo or drinksth that I shouce If I amfeelingsic ldavoidifods I feel nauseouast mayhelpor k, canI callyou? shouldI ca or vomit? HowwillI knowm Atwhat point ll? ytreatment iswo rking? Besidestakingm y atment, isth I candoto helppretre vent nauseaanedreanythingelse fromchem otherapy? vomiting
YOUDON’ TNE EDTOSUFFERNE NA USEAAND VOM ITINGFROMEDLESSLY— MOT ERA Talktoyo CHE PYMAYBE cologist,Hnurse PREVE ED preventionurtoonm akesureyoug,eotr pharmacistaboNT ut thebestpossible care.
Therea manym ythso therearo chemothreerap und ducednuatusea vom iting, or y-in nd INV. It’s im tato fact sin rderCto knowthe knowwhaptortan duringyoour youcane chemo xpect the nt. Nausea dvom rapytreatme itingfromchemo mayaffean ctyourov therapy rallhealth, fam andwork life. Talke ilylife, toyouron or pharmaci cologist,n st (ie, your urs e, theycanhelp youge healthcareteam) abo anysid eeffectsyouexpe Thisinfo tion t thetreatmentyouneedut . rien isb sedona20 cesothat behalf orma PAandEaisa surveyconducte vomitingfaHO i Inctha 1s5se mo ngpatien kefieldResearch ssedthepercepdbyWa tsreceivintgach tionsabo emotherap ut nauseaandon ytreatmen t.
MYTH Nauseaandvom itingfromchemo therapyarenorm FACT al.
Nausea ndvom itin withtreaatm ent. gfromchemotherapymaybepre vented of peoplewhoexp 83% fro mchemotherapyeriencednauseaandvom iting ought theywere withwhich theymustthlive sideeffects .
GETTHE C H OTHERAPY Easilytra EM E EF FEC TSRACKER ur sym msSsID healthcareckteyo o ucanletTyo a knowpto r what youyo Downloadit atm ’reexperiencinug. TimetoTalkCINV .com
MYTH Thereis thing I chemotheno rapy. candotoprevent nauseaandvo mitingfrom FACT
Besides tmen prevent trea ausea t, thereareseveralth gsyouca fewtipsn otohe totry: andvomitingfromchemin otherapy.Hned rearealp Besu drinkreyouare Eatan fluidsingenough slowlyddrink Av oidsweet,fried, andfatty Av oid foods odorsstrong Wear Don’t g forat clothinloose-fittin least layhfloautrs und thewisgtaaro r eatingtwo nd ordrinkingafte don’ta putstre yoursto Us ere ation machsson technlaux es,suchas musiciq orente rta inment
Brought toyou by ©217EisaiIncand els nTherapeutics(U and0H elsinnTherapeuH .S.),Inc.Allrightsres ticsin (U.S.),Inc.TheTime erved.TimetoTalkC toTalkCINVcampaig V isacollaboration nisfundedbyEisaiIN Inc™ andHelsinnTherapebetweentheHematology utics(U.S.),Inc.US0 /OncologyPharmacy 275January2017 Association,EisaiIn c,
PATIENT COMMUNICA TION CHECKLIST
WHAT YO NEEDTOUREALLY ABOUT CHEMOTHKNOW ER Y-IN DUCED NAUS EAANDAP VOMITIN G
Chemotherapy-in ducednauseaan vom iting occur me uptosevecan diatelyord ndaysaftim er treatme nt. C H E M O THER PA YN IN D U C ED NA C H E U SEA O A TA H ER D IND VO PA M YN IT -D IN G U CA C EM N D O N CC U UR SEA A VOM IT IN G C A N O CC UR W ITHIN AFTER 24 H OU RS 24 H OU RS
MYTH
Nausea isworkinag.ndvomitingaresignsthat my chemotherapy FACT
Although meanch manybelievenauseaandvomitin thecase.emotherapyisworking— that'snotg Nauseaandvom not your chem gdon otherapyisworkitin ing. ’t indicatewhether or
MYTH I don't w nt tobe aburdenbytalkin vomitinga fromchem gabout mynause otherapy. aand FACT
Your healthcarete amwantstokno Don't bea fraidtoas wwhat isconcern kyour logis pharmacis t anyque t, e, and/oringyou. stionsthoantco youmaynhuars ve.
MYTHS AND FACTS ABOUT CINV
Brought to you by
©2017 Eisai Inc and Helsinn Eisai Inc, Therapeutics and Helsinn Therapeutics
(U.S.), Inc. All rights (U.S.), Inc. reserved. The Time Time to Talk to Talk CINV CINV™ is campaign a collaboratio is funded n between by Eisai Inc the Hematology and Helsinn Therapeutics /Oncology Pharmacy (U.S.), Inc. Association, US0277 January 2017
REDEFINE PATIENT EXPECTATIONS HEAD ON BY ADDRESSING MISPERCEPTIONS ABOUT CINV Some patients believe that CINV is a side effect that they must live with when on chemotherapy. Healthcare practitioners know that this and other beliefs may not be entirely true and can impact care.
83%
nausea and vomiting of people who experienced they were side effects from chemotherapy thought with which they must live.
that my chemotherapy
not
and vomiting Although many believe nausea not mean chemotherapy is working—that's the case. indicate whether or Nausea and vomiting don’t your chemotherapy is working.
MYTH
from and by talking about my nausea I don't want to be a burden MYTH vomiting from chemotherapy. I should wait until I experience chemothe FACT nausea and rapy to talk vomiting to to MYTH FACT myhelp healthcare from several things you can do team about Besides treatment, there are it. FACT are a If I keep reporting from chemotherapy. Here side effects prevent nausea and vomiting oncologist from my chemothe will stop my few tips to try: treatment. rapy, my
There is nothing I can do to chemotherapy.
prevent nausea and vomiting
FACT
Eat and drink
Be sure you are drinking enough fluids Avoid sweet, fried, and fatty foods
Share or walk through this myth-busting tool with patients in order to ensure patients and caregivers understand that CINV may be prevented.
AFTER
HOURS
HOURS
FACT
chemotherapy may be prevented
MYTH
24
WITHIN
Nausea and vomiting are signs is working.
chemotherapy are normal.
FACT
Wear loose-fitting clothing around the waist and don’t put stress on your stomach
slowly Oncologist you. s look is concerning to know what for ways to Your healthcare team wants manage side and/or effects oncologist, nurse, with other Avoid strong Don't be afraid to ask your medicines and/or that you may have. lifestyle changes. odors pharmacist any questions By speaking up The sooner early, you help your oncologist can you lay flat for at about chemothe Don’t ask nausea and control or prevent side rapy, the vomiting from hours after least two sooner effects you can help are still manageab while they prevent it. eating or drinking le. Use relaxation techniques, such as music or entertainment
MYTH It’s normal to still feel nauseous treatment even though to prevent it, as long I’ve received as I’m not vomiting.
MYTH Nausea and vomiting aren’t through; it's not affecting a big deal. I can just me, no one push me that much—an else. d it only affects
FACT
This is a common
81%
mispercep
FACT
tion. In fact,
of patients with nausea chemothe rapy believe and vomiting from that their antinause vomiting treatment a/ is working not vomiting. as long as they’re
Nausea and vomiting nutrition, dehydratio from chemothe n, and electrolyterapy can lead to poor imbalance s.
61%
of said it caused survey responders family events. them to miss out on
YOU DON’T NEED NEEDLESSLY— TO SUFFER AND VOMITIN NAUSEA FROM CHEMOG THERAPY MAY BE PREVEN TED Talk to your oncologist, about preventi nurse, or pharmac ist chemotherapy ng nausea and vomiting possible care. to make sure you get from the best
48%
said it caused them to miss work.
GET THE CHEMO THERAPY EFFECTS SIDE TRACKER Easily track your symptom so you can s let your healthcare team you’re experien know what cing.
Download
©2017 Eis ai I between the nc and Helsinn The r ap eu t i c s Hematology/ ( U.S.) , Inc The Time Oncology . A ll r i g to Talk CINV Pharmacy campaign Association, hts reser ved. Time is funded to Talk CIN Eisai Inc, by Eisai Inc V ™ is a c o and Helsinn and Helsinn Therapeutics ll a b o r a t i o n Therapeutics (U.S.), Inc. (U.S.), Inc. US0274 January 2017
Your healthcare team is here to help.
BEFORE STARTING CHEMOTHERAPY
Provide this checklist to patients following initial
What are the possible side effects of my chemotherapy?
to equip them with the right information so that you can work together to best manage their potential side effects.
Do I have any risk factors that might make me more or less likely to have nausea and vomiting from chemotherapy?
Considering the type of chemotherapy I am receiving, how likely is it that I will experience nausea and vomiting?
PREVENTING NAUSEA AND VOMITING This section includes questions
How do you decide what treatment to use to prevent my nausea and vomiting?
FROM CHEMOTHERAPY
you can ask your healthcare team
about
medications for theAssociation, from chemotherapy. treatment of nausea and vomiting ology Pharmacy . between the Hematology/Onc is a collaboration (U.S.), Inc. US to Talk CINV™ Whichrights Helsinn Therapeutics antinausea reserved. Time and vomiting by Eisai Inc and treatment do you (U.S.), Inc. All campaign is funded If I do have nausea and/or vomiting, Talk CINVbe taking and why? and Helsinn Therapeutics Inc. The think Time toI should what should (U.S.), ©2017 Eisai Inc I do? Helsinn Therapeutics Eisai Inc, and When should I start taking my treatment?
What information would be helpful for you to have if I do experience nausea and vomiting chemotherapy?
How should I take my treatment? With this treatment, what should
I expect to happen?
What are some of the possible side effects treatment?
from
Are there certain foods or drinks that may help or that I should avoid if I feel nauseous or vomit? How will I know my treatment is working?
of my
If I am feeling sick, can I call you? At what point should I call?
Involve a caregiver and make sure the responses are written down on the notes page or in a notebook.
It is challenging to have an in-depth understanding of a patient’s experience outside of the office visit.
CHEMOTHERAPYINDUCED NAUSEA AND VOMITING CAN OCCUR
24
MYTH
MYTH
Nausea and vomiting from
Nausea and vomiting from with treatment.
GET THE CONVERSATION STARTED
Besides taking my treatment, is there anything else I can do to help prevent nausea and vomiting from chemotherapy?
YOU DON’T NEED TO SUFFER NEEDLESSLY— NAUSEA AND VOMITING FROM CHEMOTHERAPY MAY BE PREVENTED Talk to your oncologist, nurse, or pharmacist about prevention to make sure you get the best possible care.
GET THE CHEMOTHERAPY SIDE EFFECTS TRACKER Easily track your symptoms so you can let your healthcare team know what you’re experiencing. Download it at TimetoTalkCINV.com
Brought to you by
©2017 Eisai Inc and Helsinn T herapeutics ( U.S.) , Inc. All righ ts reser ved. Time to Talk CINV ™ and Helsinn Therapeutics (U.S.), is a c o ll a b o r a t i o n b e t w e e n t h e Inc. The Time to Talk CINV campaign H e m a t o l o g y /O n c o l o g y P h a r m a is funded by Eisai Inc and Helsinn c y A s s o c i a t i o n , E i s a i I n c, Therapeutics (U.S.), Inc. US0275 January 2017
CHEMOTHERAPY SIDE EFFECTS TRACKER
NAME:
CONTACT:
MEDICATIONS:
While receiving chemotherapy, it's important to track and discuss side effects, like chemotherapy-induced nausea and vomiting (CINV), with your healthcare team to prevent future episodes. Please fill in the chart below by recording your nausea level from 1 (not nauseous) to 5 (vomited). Mark with an X if you had a chemotherapy session or took your antinausea treatment that day. Fill in the other rows and use the numbered rows to track whatever else you would like, such as favorite activities. Share the results with your oncologist, nurse, or pharmacist (ie, your healthcare team).
MONTH: SEPTEMBER DAY:
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1 2 3
NAUSEA LEVEL
4 5
0
TIMES VOMITED CHEMOTHERAPY SESSION ANTINAUSEA TREATMENT
2 3
ENERGY LEVEL (1-5) 1 - L OW, 5 - HIGH
SLEEP QUALITY (1-5) 1 - NOT RESTED , 5 - RESTED
1: 2:
and Chemotherapy-induced nausea or vomiting can occur immediately up to seven days after treatment. CHEMOTHERAPYINDUCED NAUSEA AND VOMITING CAN OCCUR
AND IT STARTS WITH A CONVERSATION
Nausea and vomiting are side effects of chemotherapy that may be prevented. It’s definitely not something that should get in the way of your chemotherapy. It’s so important to have frequent h o n e s t c o nv e r s a t i o n s w i t h y o u r and healthcare team. Talking to the m a b o u t c h e m o t h e r a p y si d e e f f can lead to better care of your ec ts nausea and vomiting. In turn, that could lead to an easier journey through chemotherapy treatment.
At your next appointment, bring this page with you and take notes as you talk to your healthcare team:
ENCOURAGE PATIENTS AND THEIR CAREGIVERS TO TRACK THEIR EXPERIENCES SO THEY CAN ACCURATELY RELAY INFORMATION
WHAT YOU REALLY NEED TO KNOW ABOUT CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING
there around There are many myths out and chemotherapy-induced nausea to know the vomiting, or CINV. It’s important you can expect facts in order to know what treatment. during your chemotherapy chemotherapy Nausea and vomiting from family life, may affect your overall health, oncologist, nurse, you experience so that and work life. Talk to your team) about any side effects or pharmacist (ie, your healthcare you need. treatment they can help you get the by Wakefield Research on on a 2015 survey conducted This information is based about nausea and Inc that assessed the perceptions behalf of HOPA and Eisai receiving chemotherapy treatment. vomiting among patients
THERE ARE WAYS TO PREVENT NAUSEA AND VOMITING FROM CHEMOTHERAPY
Patients are often nervous and unsure of what to ask when starting chemotherapy.
THE
Follow up with or who have patients just starting previously on chemothe hours of leaving experienc ed CINV within rapy the office 24-48 Utilize appropriat such as patient e processes to ensure shared amongst risk factors and reports that information, the full healthcare of CINV, is team Find out how patients want office visits to be contacted (phone call following text, etc.) on mobile or home phone, email,
• History of morning sickness • History of no or low alcohol during pregnancy • Prone to motion sickness consumption • Have had chemothe rapy previously • History of anxiety • High pretreatme nt expectatio n of severe nausea
ENSURE CLEAR
NOTES
it at TimetoTa
Brought to
lkCINV.com
you by
This tracker can provide a plan for monitoring CINV and will help the healthcare team know how to best advise patients on CINV prevention. Show patients and their caregivers how to complete each step in this chemotherapy side effect tracker. Explain that it is important to understand nausea or vomiting levels compared to when chemotherapy was received and if/when they took their antiemetics. Show patients where they can mark their nausea, energy and sleep quality levels on the 1-5 scale and how they might know where they are falling on the scale.
YOU DON'T NEED TO SUFFER NEEDLESSLY—NAUSEA AND VOMITING FROM CHEMOTHERAPY MAY BE PREVENTED Talk to your oncologist, nurse, or pharmacist about prevention to make sure you get the best possible care.
MORE RESOURCES
ADDITIONAL NOTES
KEY
8/23/16 - Felt sick after breakfast
- NOT NAUSEOUS - SLIGHT LY NAUSEOUS - NAUSEOUS - VE RY NAUSEOUS - VOMITED
www.TimetoTalkCINV.com
You can download the MASCC Antiemesis Tool app at mascc.org/mat. It lets you capture information on nausea and vomiting episodes to ensure you are achieving the best control of these possible side effects. This information can be shared with your healthcare team when evaluating your treatment.
Brought to you by
©2017 Eisai Inc and Helsinn Therapeutics (U.S.), Inc. All rights reserved. Time to Talk CINV™ is a collaboration between the Hematology/Oncology Pharmacy Association, Eisai Inc, and Helsinn Therapeutics (U.S.), Inc. The Time to Talk CINV campaign is funded by Eisai Inc and Helsinn Therapeutics (U.S.), Inc. US0289 January 2017
Help your patient determine which tracker format best corresponds to their chemotherapy regimen. NAME: CONTACT: MEDICATIONS:
CHEMOTHERAPY SIDE EFFECTS TRACKER While receiving chemotherapy, it's important to track and discuss side effects, like chemotherapy-induced nausea and vomiting (CINV), with your healthcare team to prevent future episodes. This tracker will help you start the conversation. Each day, mark your nausea level from 1 (not nauseous) to 5 (vomited), and complete the other rows in the column. Fill in the bubbles to the right if you had a chemotherapy session or took your antinausea treatment that day.
Nausea Level
Date
1
2
3
8/23/16
4
5
Times Vomited
1
KEY
Diet
Light breakfast Walked 30 min
MORE RESOURCES
- NOT NAUSEOUS - SLIGHT LY NAUSEOUS - NAUSEOUS - VE RY NAUSEOUS - VOMITED
Activity
www.TimetoTalkCINV.com
Energy Sleep Level (1-5) Quality (1-5) 1 - L OW 5 - HIGH
1 - NOT RESTED 5 - RESTED
3
2
Notes
YOU DON'T NEED TO SUFFER NEEDLESSLY—NAUSEA AND VOMITING FROM CHEMOTHERAPY MAY BE PREVENTED TALK TO YOUR ONCOLOGIST, NURSE, OR PHARMACIST ABOUT PREVENTION TO MAKE SURE YOU GET THE BEST POSSIBLE CARE
Chemo Antinausea Session Treatment
Felt sick after breakfast
You can download the MASCC Antiemesis Tool app at mascc.org/mat. It lets you capture information on nausea and vomiting episodes to ensure you are achieving the best control of these possible side effects. This information can be shared with your healthcare team when evaluating your treatment. Brought to you by
©2017 Eisai Inc and Helsinn Therapeutics (U.S.), Inc. All rights reserved. Time to Talk CINV™ is a collaboration between the Hematology/Oncology Pharmacy Association, Eisai Inc, and Helsinn Therapeutics (U.S.), Inc. The Time to Talk CINV campaign is funded by Eisai Inc and Helsinn Therapeutics (U.S.), Inc. US0273 January 2017
ADDITIONAL TIPS FOR COMMUNICATING ABOUT CINV WITH PATIENTS Explain the term CINV — most patients are used to hearing nausea and vomiting after chemotherapy so let them know that the acronym CINV means the same thing Remind them about the different periods of time when CINV can occur — tell patients that CINV can occur within 24 hours of receiving chemotherapy or during the days following chemotherapy but that both may be prevented Identify the member of the healthcare team whom patients should reach out to when they experience CINV based on the setup of your institution or facility Make these tools your own and embrace them as an approach to helping improve patient care and outcomes.
PATIENTS DON’T NEED TO SUFFER NEEDLESSLY.
TALK TO YOUR PATIENTS ABOUT THE PREVENTION OF CINV AND VISIT TIMETOTALKCINV.COM to print or use these tools digitally, email them to your patients and share them online via social media. ©2017 Eisai Inc. and Helsinn Therapeutics (U.S.), Inc. All rights reserved. Time to Talk CINV™ is a collaboration between the Hematology/Oncology Pharmacy Association, Eisai Inc., and Helsinn Therapeutics (U.S.), Inc. The Time to Talk CINV campaign is funded by Eisai Inc. and Helsinn Therapeutics (U.S.), Inc. US0335.
