Toolkit Infographic

---

Suffering from chemotherapy-induced nausea and vomiting? You may be doing so needlessly If you or a loved one is suffering from chemotherapy-induced nausea and vomiting (CINV), you should know that this side effect may be prevented. Even one patient suffering from nausea and vomiting due to chemotherapy is one too many. Use the Time to Talk CINVTM toolkit to ensure you are receiving the best possible care while going through chemotherapy.

Introducing the Time to Talk CINV Toolkit MYTH FACT

Use the Myths and Facts about CINV tool to better understand the facts about chemotherapy-induced nausea and vomiting.

WHAT YOU REALLY NEED TO KNOW ABOUT CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING

Many do not know the facts about this side effect and how it can impact overall health. Make sure you don’t have any false assumptions and are well informed about what you should — or should not — expect when receiving chemotherapy.

FACT

83%

MYTH

prevent nausea and vomiting

not

HOURS

MYTH It’s normal to still feel nauseous treatment even though to prevent it, as long I’ve received as I’m not vomiting.

MYTH Nausea and vomiting aren’t through; it's not affecting a big deal. I can just me, no one push me that much—an else. d it only affects

that my chemotherapy FACT

This is a common

mispercep

FACT

tion. In fact,

Nausea and vomiting nutrition, dehydratio from chemothe n, and electrolyterapy can lead to poor imbalance s.

of and vomiting Although many believe nausea 81% not patients with nausea chemothe rapy believe and vomiting from mean chemotherapy is working—that's that their antinause vomiting treatment the case. a/ is working not vomiting. as long as indicate whether or they’re Nausea and vomiting don’t your chemotherapy is working.

61%

of said it caused survey responders family events. them to miss out on

YOU DON’T NEED NEEDLESSLY— TO SUFFER AND VOMITIN NAUSEA FROM CHEMOG

48%

said it caused them to miss work.

and about my nausea THERAP by talkingMAY Y I don't want to be a burden BE PREVEN TED vomiting from chemotherapy.

FACT

GET THE CHEMO THERAPY EFFECTS SIDE TRACKER

Talk to your oncologist, about preventi nurse, or pharmac ist chemotherapy ng nausea and vomiting possible care. to make sure you get from the best

FACT

Eat and drink slowly

Easily track your symptom so you can s let your healthcare team you’re experien know what cing.

you. to know what is concerning Your healthcare team wants oncologist, nurse, and/or Don't be afraid to ask your that you may have. pharmacist any questions

Avoid strong odors

Avoid sweet, fried, and fatty foods

24

WITHIN

MYTH

from

to help several things you can do Besides treatment, there are are a from chemotherapy. Here prevent nausea and vomiting few tips to try: Be sure you are drinking enough fluids

The AFTER sooner you ask about chemothe rapy, the sooner nausea and vomiting HOURS from you can help prevent it.

24

FACT

chemotherapy may be prevented

There is nothing I can do to chemotherapy.

FACT

Oncologist s look for ways to manage side effects with medicines and/or lifestyleother By speaking up early, you changes. help your oncologist can control or prevent side effects are still manageab while they le.

CHEMOTHERAPYINDUCED NAUSEA AND VOMITING CAN OCCUR

CHEMOTHERAPYINDUCED NAUSEA AND VOMITING CAN OCCUR

Nausea and vomiting are signs is working.

chemotherapy are normal.

nausea and vomiting of people who experienced they were side effects from chemotherapy thought with which they must live.

MYTH If I keep reporting side effects oncologist from my chemothe will stop my treatment. rapy, my

and Chemotherapy-induced nausea or vomiting can occur immediately up to seven days after treatment.

MYTH

MYTH

Nausea and vomiting from

Nausea and vomiting from with treatment.

MYTH I should wait until I experience chemothe nausea rapy to talk to my healthcare and vomiting from team about it. FACT

there around There are many myths out and chemotherapy-induced nausea to know the vomiting, or CINV. It’s important you can expect facts in order to know what treatment. during your chemotherapy chemotherapy Nausea and vomiting from family life, may affect your overall health, oncologist, nurse, e so t hat and work life. Talk to your side ef fects you experienc althcare team) about any or pharmacist (ie, your he treatment you need. they can help you get the by Wakefield Research on on a 2015 survey conducted This information is based about nausea and Inc that assessed the perceptions behalf of HOPA and Eisai receiving chemotherapy treatment. vomiting among patients

Download

Don’t lay flat for at least two hours after eating or drinking

Wear loose-fitting clothing around the waist and don’t put stress on your stomach

©2017 Eisai Inc and Helsinn between the Therapeutics Hematology/ (U.S.), Inc. The Time Oncology All rights to Talk CINV Pharmac y reserved. campaign A s s o cia t io Time to Talk is funded CINV™ is by Eisai Inc n, Eisai Inc, and He a collaboration lsi n n and Helsinn Therapeutics Therapeutics (U.S.), Inc. (U.S.), Inc. US0274 January 2017

Ask the questions provided in the Patient Communication Checklist during your appointment with your healthcare team to start an open and thorough conversation about side effects of chemotherapy. Bring the notes sheet to your visit to write down important information to remember later.

it at TimetoTa lkCINV.com

Use relaxation techniques, such as music or entertainment

Brought to

you by

NOTES THERE ARE WAYS TO PREVENT NAUSEA AND VOMITING FROM CHEMOTHERAPY

AND IT STARTS WITH A CONVERSATION

Nausea and vomiting are side effects of chemotherapy that may be prevented. It’s definitely not s o m e t h i n g t h a t s h o u l d ge t i n t h e way of your chemotherapy. It’ s so impor tant to have frequen h o n e s t c o nv e r s a t i o n s w i t h y o u r t an d healthcare team. Talking to the m a b o u t c h e m o t h e r a p y si d e e f f can lead to better care of your ects nausea and vomiting. In turn, that could lead to an easier journey through chemotherapy treatment.

GET THE CONVERSATION STARTED Your healthcare team is here to help. At your next appointment, bring

this page with you and take notes as you talk to your

healthcare team:

BEFORE STARTING CHEMOTHERAPY What are the possible side effects of my chemotherapy?

Do I have any risk factors that might make me more or less likely to have nausea and vomiting from chemotherapy?

Considering the type of chemotherapy I am receiving, how likely is it that I will experience nausea and vomiting?

PREVENTING NAUSEA AND VOMITING

How do you decide what treatment to use to prevent my nausea and vomiting?

FROM CHEMOTHERAPY

This section includes questions you can ask your healthcare team about medications for the treatment from chemotherapy. of nausea and vomiting

Getting answers to these questions can help ensure you have the all the right information you need when it comes to your treatment.

Track your side effects, such as frequency of nausea and vomiting, energy level and quality of sleep, with the Chemotherapy Side Effect Tracker. Work with your healthcare team to decide if the 10 day tracker or 30 day tracker works better with your treatment schedule and history of, or risk for, these side effects.

Which antinausea and vomiting treatment do you think I should be taking and why?

What information would be helpful for you to have if I do experience nausea and vomiting chemotherapy?

from

Are there certain foods or drinks that may help or that I should avoid if I feel nauseous or vomit? How will I know my treatment is working?

If I am feeling sick, can I call you? At what point should I call?

Besides taking my treatment, is there anything else I can do to help prevent nausea and vomiting from chemotherapy?

gy Pharmacy Association, .

between the Hematology/Oncolo is a collaboration (U.S.), Inc. US Time to Talk CINV™ Helsinn Therapeutics rights reserved. by Eisai Inc and (U.S.), Inc. All campaign is funded and Helsinn Therapeutics Inc. The Time to Talk CINV (U.S.), ©2017 Eisai Inc Helsinn Therapeutics Eisai Inc, and

YOU DON’T NEED TO SUFFER NEEDLESSLY— NAUSEA AND VOMITING FROM CHEMOTHERAPY MAY BE PREVENTED Talk to your oncologist, nurse, or pharmacist about prevention to make sure you get the best possible care.

GET THE CHEMOTHERAPY SIDE EFFECTS TRACKER Easily track your symptoms so you can let your healthcare team know what you’re experiencing. Download it at TimetoTalkCINV.com

Brought to you by

©2017 Eisai Inc and Helsinn Therapeutics (U.S.), Inc. All rights reserved. and Helsinn Therapeutics ( U.S Time to Talk CINV™ is a collaboration .) , Inc. The Time to Talk CINV c between the Hematology/Oncology a m p ai g n is f u n d e d b y E is a i I n c Pharmacy Association, Eisai Inc, and Helsinn Ther apeutics ( U.S .) , Inc. US0275 Januar y 2017

CHEMOTHERA PY SIDE

EFFECTS TRACK ER

While receiving chemotherapy, it's important and vomiting (CINV), with your to track and discuss healthcare team your nausea level to prevent future side effects, like chemotherapy-in from antinausea treatment 1 (not nauseous) to 5 episodes. Please duced nausea (vomited). Mark fill in the chart that day. Fill in with an X if you such as favorite the other rows had a chemotherapy below by recording activities. Share and use the numbered the results with session or took rows to track your your oncologist, nurse, or pharmacist whatever else you would like, 1 (ie, your healthcare 2 3 4 team). 5 6

NAME: MEDICATIONS:

CONTACT:

MONTH: SEPTEMBER DAY:

7

1

8

9

10

11

12

13

14

15

2 NAUSEA LEVEL

16

17

18

19

20

21

22

23

24

25

26

27

3

28

29

4 5 TIMES VOMITED

0

CHEMOTHERAPY SESSION ANTINAUSEA TREATMENT ENERGY LEVEL

(1-5)

SLEEP QUALITY

(1-5)

1 - L OW, 5 - HIGH 1 - NOT RESTED

, 5 - RESTED

2 3

1: 2:

S TRACKER Y SIDE EFFECT YOU DON'T NEED CHEMOTHERAP

NAME: CONTACT: MEDICATIONS:

like TO SUFFER NEEDLESS side effects, to to prevoncologist, LY—NAUS e n t f u tu r e track and discuss cTalk eam your it's important to nurse, or pharmacist EA AND VOMITING FROM ur h ea l t h a r e t chemotherapy, (CINV), with yo KEY mark your nausea level from CHEMOTHERAPY about prevention While receiving a and vomiting to Each day, in duce d na u se to make sure Fill in the bubbles chemotherapyyou start the conversation. in the column. you get the best MAY BE PREVENTED tracker will help NOT NAUSEOUS the other- rows ADDITIONAL NOTES ent that day. possible care. episodes. This and complete n au s e a t r e a t m to 5 (vomited), 8/23/16 - Felt sick r to o k y o u r a n t i 1 (not nauseous) Chemo Antinausea e r a p y s e s si o n o - SLIGHT LY NAUSEOUS after breakfast Sleep h a d a c h e m ot h Energy t h e r i g h t i f yo u MORE RESOURCES Session Treatment Notes (1-5) - NAUSEOUS Level (1-5) Quality 1 - NOT RESTED Activity 1 - L OW Times 5 - RESTED Diet 5 - HIGH - VE Nausea Level Vomited Date

1

2

3

4

5

RY NAUSEOUS

- VOMITED

1

Light breakfast

Walked 30 min

3

2

Felt sick after breakfast

You can down lo a d t h e M A S C C A n t i e m e sis v o m i t i n g e p is o Tool app at mascc.org/mat. d es shared with your to ensure you are achieving It lets you capture t he b es t c o nt r healthcare team information on ol of t h es e p o when evaluating nausea and s si b l e si

8/23/16

By keeping track of these side effects when you experience them and sharing the completed tracker at your appointments, you can easily keep your healthcare team informed and work together to determine the best steps for moving forward.

If I do have nausea and/or vomiting, what should I do?

When should I start taking my treatment? How should I take my treatment? With this treatment, what should I expect to happen? What are some of the possible side effects of my treatment?

your treatment. d e ef f e c t s. T h ©2017 Eisai I is i n f o r m a t i o n n c an c an b e The Time to Talk d Helsinn Ther apeutics ( U. S. ) , I n CINV campaign is funded by Eisai c. All rights reser ved. Time to Talk CINV ™ Inc and Helsinn is a c o Therapeutics (U.S.), Inc. US0289 llabor ation bet ween the H e m a t o l o g y /O n January 2017 c

KEY

MORE RESOURCES

- NOT NAUSEOUS - SLIGHT LY NAUSEOUS - NAUSEOUS - VE RY NAUSEOUS - VOMITED

www.TimetoTalkCINV.com

TO SUFFER YOU DON'T NEED AND NEEDLESSLY—NAUSEA CHEMOTHERAPY VOMITING FROMPREVENTED MAY BE ONCOLOGIST, TALK TO YOUR NURSE, OR PHARMACIST TO ABOUT PREVENTION GET MAKE SURE YOU CARE THE BEST POSSIBLE

between the Hematology/Oncol is a collaboration 2017 Time to Talk CINV™ rights reserved. Inc. US0273 January (U.S.), Inc. All Therapeutics (U.S.), and Helsinn Therapeutics by Eisai Inc and Helsinn ©2017 Eisai Inc is funded CINV campaign The Time to Talk

www.TimetoTa lkCINV.com Brought to you olo g y Ph ar m a

by

c y A s so ciatio n

, E i s a i I n c, a n

d H e ls i n n T h e

Tool the MASCC Antiemesis You can download It lets you capture app at mascc.org/mat. and vomiting episodes nausea control of information on achieving the best to ensure you are effects. This information side en these possible h c ar e te a m w h w i t h y o u r h e al t c an b e shar e d treatment. evaluating your Brought to you

by

Therapeutics Inc, and Helsinn Association, Eisai ogy Pharmacy

(U.S.), Inc.

CINV is a potentially serious, preventable, side effect of chemotherapy that, when untreated, can lead to missing out on family events and even wanting to avoid future cancer treatments. By learning about this side effect and talking with your healthcare team, you can help improve your treatment experience.

To access the Time to Talk CINV toolkit, developed with the help of patients like you, and additional resources about this side effect of chemotherapy, please visit TimeToTalkCINV.com.

©2017 Eisai Inc. and Helsinn Therapeutics (U.S.), Inc. All rights reserved. Time to Talk CINV™ is a collaboration between the Hematology/Oncology Pharmacy Association, Eisai Inc., and Helsinn Therapeutics (U.S.), Inc. The Time to Talk CINV campaign is funded by Eisai Inc. and Helsinn Therapeutics (U.S.), Inc. US0336 February 2017

r apeutics ( U.S

. ) , I n c.

30

31